Garcia, SilviaRódenas-Munar, MarinaBohn, TorstenKemperman, AstridRodrigues, DanielaEvers, SuzanLamy, ElsaPerez-Jimenez, MariaForberger, SarahOnorati, Maria GiovannaDevecchi, AndreaMagistris, Tiziana deHalimi, JihanIvanova, YoannaDoychinov, BoykoBouzas, CristinaTur, Josep A.2025-12-172025-12-172025-12-15García, S., Ródenas-Munar, M., Bohn, T., Kemperman, A., Rodrigues, D., Evers, S., Lamy, E., Pérez-Jiménez, M., Forberger, S., Onorati, M. G., Devecchi, A., Magistris, T. D., Halimi, J., Ivanova, Y., Doychinov, B., Bouzas, C., Tur, J. A., García, S., Ródenas-Munar, M., … Tur, J. A. (2025). Empowering Healthy Lifestyle Behavior Through Personalized Intervention Portfolios Using a Healthy Lifestyle Recommender System to Prevent and Control Obesity in Young Adults: Pilot Study Protocol from the HealthyW8 Project. Journal of Personalized Medicine, 15(12). https://doi.org/10.3390/jpm151206252075-4426https://doi.org/10.3390/jpm15120625https://hdl.handle.net/10532/8050Background: Rising obesity rates among young adults increase long-term health risks, especially cardiometabolic conditions such as type 2 diabetes mellitus. Digital interventions can offer scalable solutions to promote and support healthy behaviors by integrating personalized diet, physical activity promotion, and behavioral support. Objective: To assess the feasibility, user friendliness, adherence, and satisfaction of the Healthy Lifestyle Recommender System (HLRS). Secondary outcomes will include measures of metabolic health and obesity. Methods: A 3-month, single-arm pilot study conducted across European countries, including Bulgaria, Germany, Italy, Netherlands, Portugal, and Spain, enrolling 351 young adults (18–25 years old, BMI 18.5–29.9 kg/m2). The intervention includes a mobile app for meal planning (Nutrida v.1), gamified physical activity encouragement (GameBus), and real-time monitoring via a wearable smartwatch device. Primary outcomes are adherence and engagement, measured through app usage and participant feedback; secondary outcomes include anthropometry, physical activity, dietary patterns, psychological well-being, and selected biomarkers of metabolic health. Expected Outcomes: Improved engagement is expected to enhance lifestyle behaviors, supporting weight management and overall well-being. Findings will guide future large-scale interventions. Conclusions: This study will contribute to minimizing the impact of obesity in Europe.enAttribution-NonCommercial-NoDerivs 3.0 Spaintexto2025-12-1710.3390/jpm15120625Teoría de los juegosSaludTecnología de la informaciónObesityPrevención de enfermedadesSalud y bienestar