Please use this identifier to cite or link to this item: http://hdl.handle.net/10532/1598
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dc.contributor.authorDervishi, Eldaes_ES
dc.contributor.authorSerrano, Carmenes_ES
dc.contributor.authorJoy Torrens, Margalidaes_ES
dc.contributor.authorSerrano Noreña, Magdalenaes_ES
dc.contributor.authorRodellar Penella, Clementinaes_ES
dc.contributor.authorCalvo Lacosta, Jorge Hugoes_ES
dc.date.accessioned2011-06-14T14:56:25Zes_ES
dc.date.available2011-06-14T14:56:25Zes_ES
dc.date.issued2010es_ES
dc.identifier.citationDervishi, Elda; Serrano, Carmen; Joy, Margalida; Serrano, Malena; Rodellar, Clementina; Calvo, Jorge H. "Effect of the feeding system on the fatty acid composition, expression of the Δ9-desaturase,Peroxisome Proliferator-Activated Receptor Alpha, Gamma, and Sterol Regulatory Element Binding Protein 1 genes in the semitendinous muscle of light lambs of the Rasa Aragonesa breed". BMC Veterinary Research. 2010, vol. 6, art. nº 40, p. 1-11es_ES
dc.identifier.urihttp://hdl.handle.net/10532/1598es_ES
dc.description.abstractBackground: Conjugated linoleic acids (CLAs) are receiving increasing attention because of their beneficial effects on human health, with milk and meat products derived from ruminants as important sources of CLA in the human diet. SCD gene is responsible for some of the variation in CLA concentration in adipose tissues, and PPARg, PPARa and SREBP1 genes are regulator of SCD gene. The aim of this work was to evaluate the effect of the feeding system on fatty acid composition, CLA content and relative gene expression of Δ9-desaturase (SCD), Peroxisome Proliferator-Activated Receptor Gamma (PPARg), Peroxisome Proliferator-Activated Receptor Alpha, (PPARa) and Sterol Regulatory Element Binding Protein (SREBP1) in Rasa Aragonesa light lambs in semitendinous muscle. Fortyfour single-born male lambs were used to evaluate the effect of the feeding system, varying on an intensity gradient according to the use of concentrates: 1. grazing alfalfa, 2. grazing alfalfa with a supplement for lambs, 3. indoor lambs with grazing ewes and 4. drylot. Results: Both grazing systems resulted in a higher concentration of vaccenic acid (VA), CLA, CLA/VA acid ratio, and a lower oleic content, oleic acid (C18:1)/stearic acid (C18:0) ratio, PUFA n-6/n-3 ratio and SCD expression compared to other diets. In addition feeding system affected the fatty acid composition and SCD expression, possibly due to CLA concentration or the PUFA n-6/n-3 ratio. Both expression of the SCD gene and the feeding system were important factors affecting CLA concentration in the animal’s semitendinous muscle. PPARg, PPARa and SREBP1 expression seemed to be unaffected by the feeding system. Although no significant results were found, PPARg, PPARa and SREBP1 showed similar expression pattern as SCD. Moreover, the correlation results between SCD expression and PPARg (p < 0.01), as well as SREBP1 (p < 0.01) expression, may suggest that these genes were affecting SCD expression in a different way. Conclusions: The data indicated that the feeding system is the main factor affecting the fatty acid composition and SCD gene expression, which is also affected by CLA and possibly by n-6/n-3 PUFAs.es_ES
dc.language.isoenes_ES
dc.subject.otherRaza Rasa aragonesaes_ES
dc.subject.otherAlimentación de los animaleses_ES
dc.subject.otherOvinoses_ES
dc.subject.otherÁcidos grasoses_ES
dc.subject.otherADNes_ES
dc.subject.otherProducción y sanidad animales_ES
dc.titleEffect of the feeding system on the fatty acid composition, expression of the Δ9-desaturase,Peroxisome Proliferator-Activated Receptor Alpha, Gamma, and Sterol Regulatory Element Binding Protein 1 genes in the semitendinous muscle of light lambs of the Rasa Aragonesa breedes_ES
dc.typeArticlees_ES
dc.relation.publisherversionhttp://www.biomedcentral.com/1746-6148/6/40es_ES
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