Por favor, use este identificador para citar o enlazar este ítem:
http://hdl.handle.net/10532/6492Registro completo de metadatos
| Campo DC | Valor | Idioma |
|---|---|---|
| dc.contributor.author | Tejedor Calvo, Eva | es_ES |
| dc.contributor.author | Morales, Diego | es_ES |
| dc.contributor.author | Morillo, Laura | es_ES |
| dc.contributor.author | Vega, Laura | es_ES |
| dc.contributor.author | Caro, Mercedes | es_ES |
| dc.contributor.author | Ribeiro Smiderle, Fhernanda | es_ES |
| dc.contributor.author | Iacomini, Marcello | es_ES |
| dc.contributor.author | Marco Montori, Pedro | es_ES |
| dc.contributor.author | Soler Rivas, Cristina | es_ES |
| dc.date.accessioned | 2023-07-18T07:35:00Z | - |
| dc.date.available | 2023-07-18T07:35:00Z | - |
| dc.date.issued | 2023 | es_ES |
| dc.identifier.citation | Foods, 2023, 12, 14, 2724-NA | - |
| dc.identifier.issn | 23048158 | - |
| dc.identifier.uri | http://hdl.handle.net/10532/6492 | - |
| dc.description.abstract | An optimized PLE method was applied to several truffle species using three different solvent mixtures to obtain bioactive enriched fractions. The pressurized water extracts contained mainly (1 ? 3),(1 ? 6)-?-D-glucans, chitins, and heteropolymers with galactose and mannose in their structures. The ethanol extracts included fatty acids and fungal sterols and others such as brassicasterol and stigmasterol, depending on the species. They also showed a different fatty acid lipid profile depending on the solvent utilized and species considered. Ethanol:water extracts showed interesting lipids and many phenolic compounds; however, no synergic extraction of compounds was noticed. Some of the truffle extracts were able to inhibit enzymes related to type 2 diabetes; pressurized water extracts mainly inhibited the ?-amylase enzyme, while ethanolic extracts were more able to inhibit ?-glucosidase. Tuber brumale var. moschatum and T. aestivum var. uncinatum extracts showed an IC50 of 29.22 mg/mL towards ?-amylase and 7.93 mg/mL towards ?-glucosidase. Thus, use of the PLE method allows o bioactive enriched fractions to be obtained from truffles with antidiabetic properties. | en |
| dc.description.sponsorship | This research was funded by the fellowship Ibercaja-CAI Estancias de Investigación number CA 1/20. The research leading to these results has received funding from the European Union under “Horizon 2020—the Framework Programme for Research and Innovation (2014–2020)”. Grant Agreement of the Project: “Innovation in truffle cultivation, preservation, processing and wild truffle resources management”, INTACT, Project number 101007623. | es_ES |
| dc.language.iso | en | es_ES |
| dc.relation.uri | https://doi.org/10.3390/foods12142724 | es_ES |
| dc.rights | Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Spain | - |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/es/ | - |
| dc.subject.other | Amilasas | - |
| dc.subject.other | Beta-Glucanos | - |
| dc.subject.other | Diabetes | - |
| dc.subject.other | Ésteres De Los Ácidos Grasos | - |
| dc.subject.other | Esteroles | - |
| dc.subject.other | Glucosidasa | - |
| dc.subject.other | TUBERACEAE | - |
| dc.title | Pressurized Liquid (PLE) Truffle Extracts Have Inhibitory Activity on Key Enzymes Related to Type 2 Diabetes (α-Glucosidase and α-Amylase) | en |
| dc.type | Journal Contribution | * |
| dc.date.updated | 2023-07-18T07:21:56Z | - |
| dc.bibliographicCitation.volume | 12 (14) | es_ES |
| dc.bibliographicCitation.stpage | 2724 | es_ES |
| dc.subject.agrovoc | Trufa (hongo) | es |
| dc.subject.agrovoc | Glucosidasa | es |
| dc.subject.agrovoc | Amilasas | es |
| dc.subject.agrovoc | Acido graso (de configuración) trans | es |
| dc.subject.agrovoc | Ergosterol | es |
| dc.subject.agrovoc | Beta-glucanos | es |
| dc.subject.agrovoc | Diabetes | en |
| dc.description.other | truffles | en |
| dc.description.other | β-D-glucans | en |
| dc.description.other | ergosterol | en |
| dc.description.other | fatty acids | en |
| dc.description.other | antidiabetic | en |
| dc.description.other | amylase | en |
| dc.description.other | glucosidase | en |
| dc.relation.references | Yaribeygi, H.; Atkin, S.L.; Pirro, M.; Sahebkar, A. A Review of the Anti-inflammatory Properties of Antidiabetic Agents Providing Protective Effects against Vascular Complications in Diabetes. J. Cell Physiol. 2019, 234, 8286–8294. [Google Scholar] [CrossRef] [PubMed] Blaak, E.E.; Antoine, J.-M.; Benton, D.; Björck, I.; Bozzetto, L.; Brouns, F.; Diamant, M.; Dye, L.; Hulshof, T.; Holst, J.J.; et al. Impact of Postprandial Glycaemia on Health and Prevention of Disease. Obes. Rev. 2012, 13, 923–984. [Google Scholar] [CrossRef] [PubMed] Xiong, M.; Huang, Y.; Liu, Y.; Huang, M.; Song, G.; Ming, Q.; Ma, X.; Yang, J.; Deng, S.; Wen, Y.; et al. Antidiabetic Activity of Ergosterol from Pleurotus Ostreatus in KK-A y Mice with Spontaneous Type 2 Diabetes Mellitus. Mol. Nutr. Food Res. 2018, 62, 1700444. [Google Scholar] [CrossRef] Stojkovic, D.; Smiljkovic, M.; Ciric, A.; Glamoclija, J.; Van Griensven, L.; Ferreira, I.C.F.R.; Sokovic, M. An Insight into Antidiabetic Properties of Six Medicinal and Edible Mushrooms: Inhibition of α-Amylase and α-Glucosidase Linked to Type-2 Diabetes. S. Afr. J. Bot. 2019, 120, 100–103. [Google Scholar] [CrossRef] Oliach, D.; Vidale, E.; Brenko, A.; Marois, O.; Andrighetto, N.; Stara, K.; Mart, J.; Arag, D.; Colinas, C.; Bonet, A. Truffle Market Evolution: An Application of the Delphi Method. Forests 2021, 12, 1174. [Google Scholar] [CrossRef] Tejedor-Calvo, E.; Morales, D.; Marco, P.; Sánchez, S.; Garcia-Barreda, S.; Smiderle, F.R.; Iacomini, M.; Villalva, M.; Santoyo, S.; Soler-Rivas, C. Screening of Bioactive Compounds in Truffles and Evaluation of Pressurized Liquid Extractions (PLE) to Obtain Fractions with Biological Activities. Food Res. Int. 2020, 132, 109054. [Google Scholar] [CrossRef] Patel, S.; Rauf, A.; Khan, H.; Khalid, S.; Mubarak, M.S. Potential Health Benefits of Natural Products Derived from Truffles: A Review. Trends Food Sci. Technol. 2017, 70, 1–8. [Google Scholar] [CrossRef] Morales, D.; Smiderle, F.R.; Villalva, M.; Abreu, H.; Rico, C.; Santoyo, S.; Iacomini, M.; Soler-Rivas, C. Testing the Effect of Combining Innovative Extraction Technologies on the Biological Activities of Obtained β-Glucan-Enriched Fractions from Lentinula edodes. J. Funct. Foods 2019, 60, 103446. [Google Scholar] [CrossRef] Morales, D.; Tejedor-Calvo, E.; Jurado-Chivato, N.; Polo, G.; Tabernero, M.; Ruiz-Rodríguez, A.; Largo, C.; Soler-Rivas, C. In Vitro and In Vivo Testing of the Hypocholesterolemic Activity of Ergosterol- and β-Glucan-Enriched Extracts Obtained from Shiitake Mushrooms (Lentinula edodes). Food Funct. 2019, 10, 7325–7332. [Google Scholar] [CrossRef] Palanisamy, M.; Aldars-García, L.; Gil-Ramírez, A.; Ruiz-Rodríguez, A.; Marín, F.R.; Reglero, G.; Soler-Rivas, C. Pressurized Water Extraction of β-Glucan Enriched Fractions with Bile Acids-Binding Capacities Obtained from Edible Mushrooms. Biotechnol. Prog. 2014, 30, 391–400. [Google Scholar] [CrossRef] Tejedor-calvo, E.; García-Barreda, S.; Sánchez, S. Application of Pressurized Liquid Extractions to Obtain Bioactive Compounds from Tuber aestivum and Terfezia claveryi. Foods 2022, 11, 298. [Google Scholar] [CrossRef] [PubMed] Gil-Ramírez, A.; Caz, V.; Martin-Hernandez, R.; Marín, F.R.; Largo, C.; Rodríguez-Casado, A.; Tabernero, M.; Ruiz-Rodríguez, A.; Reglero, G.; Soler-Rivas, C. Modulation of Cholesterol-Related Gene Expression by Ergosterol and Ergosterol-Enriched Extracts Obtained from Agaricus bisporus. Eur. J. Nutr. 2016, 55, 1041–1057. [Google Scholar] [CrossRef] [PubMed] Wang, Q.; Cheng, J.; Wang, L.; Yan, S.; Wang, R.; Zhang, H.; Shao, H.; Yang, X. Valorization of Spent Shiitake Substrate for Recovery of Antitumor Fungal Sterols by Ultrasound-Assisted Extraction. J. Food Biochem. 2018, 42, e12602. [Google Scholar] [CrossRef] Kobori, M.; Yoshida, M.; Ohnishi-Kameyama, M.; Shinmoto, H. Ergosterol Peroxide from an Edible Mushroom Suppresses Inflammatory Responses in RAW264.7 Macrophages and Growth of HT29 Colon Adenocarcinoma Cells. Br. J. Pharmacol. 2007, 150, 209–219. [Google Scholar] [CrossRef] Sommer, K.; Vetter, W. Gas Chromatography with Mass Spectrometry Detection and Characterization of 27 Sterols in Two Truffle (Tuber) Species. J. Food Compos. Anal. 2020, 94, 103650. [Google Scholar] [CrossRef] Beara, I.; Majkić, T.; Torović, L. Bioguided Design of New Black Truffle (Tuber aestivum Vittad.) Product Enriched with Herbs and Spices. LWT 2021, 138, 110637. [Google Scholar] [CrossRef] Bhotmange, D.U.; Wallenius, J.H.; Singhal, R.S.; Shamekh, S.S. Enzymatic Extraction and Characterization of Polysaccharide from Tuber aestivum. Bioact. Carbohydr. Diet. Fibre 2017, 10, 1–9. [Google Scholar] [CrossRef] Deveci, E.; Çayan, F.; Tel-Çayan, G.; Duru, M.E. Inhibitory Activities of Medicinal Mushrooms on α-Amylase and α-Glucosidase-Enzymes Related to Type 2 Diabetes. S. Afr. J. Bot. 2021, 137, 19–23. [Google Scholar] [CrossRef] Kosanić, M.; Ranković, B.; Stanojković, T.; Radović-Jakovljević, M.; Ćirić, A.; Grujičić, D.; Milošević-Djordjević, O. Craterellus cornucopioides Edible Mushroom as Source of Biologically Active Compounds. Nat. Prod. Commun. 2019, 14, 1934578X1984361. [Google Scholar] [CrossRef] Bach, F.; Zielinski, A.A.F.; Helm, C.V.; Maciel, G.M.; Pedro, A.C.; Stafussa, A.P.; Ávila, S.; Haminiuk, C.W.I. Bio Compounds of Edible Mushrooms: In Vitro Antioxidant and Antimicrobial Activities. LWT 2019, 107, 214–220. [Google Scholar] [CrossRef] Zhang, T.; Jayachandran, M.; Ganesan, K.; Xu, B. Black Truffle Aqueous Extract Attenuates Oxidative Stress and Inflammation in STZ-Induced Hyperglycemic Rats via Nrf2 and NF-ΚB Pathways. Front. Pharmacol. 2018, 9, 1257. [Google Scholar] [CrossRef] Smiderle, F.R.; Morales, D.; Gil-Ramírez, A.; de Jesus, L.I.; Gilbert-López, B.; Iacomini, M.; Soler-Rivas, C. Evaluation of Microwave-Assisted and Pressurized Liquid Extractions to Obtain β-D-Glucans from Mushrooms. Carbohydr. Polym. 2017, 156, 165–174. [Google Scholar] [CrossRef] Gil-Ramírez, A.; Aldars-García, L.; Palanisamy, M.; Jiverdeanu, R.M.; Ruiz-Rodríguez, A.; Marín, F.R.; Reglero, G.; Soler-Rivas, C. Sterol Enriched Fractions Obtained from Agaricus bisporus Fruiting Bodies and By-Products by Compressed Fluid Technologies (PLE and SFE). Innov. Food Sci. Emerg. Technol. 2013, 18, 101–107. [Google Scholar] [CrossRef] Rivera, C.S.; Blanco, D.; Marco, P.; Oria, R.; Venturini, M.E. Effects of Electron-Beam Irradiation on the Shelf Life, Microbial Populations and Sensory Characteristics of Summer Truffles (Tuber aestivum) Packaged under Modified Atmospheres. Food Microbiol. 2011, 28, 141–148. [Google Scholar] [CrossRef] [PubMed] Morales, D.; Smiderle, F.R.; Piris, A.J.; Soler-Rivas, C.; Prodanov, M. Production of a β-d-Glucan-Rich Extract from Shiitake Mushrooms (Lentinula edodes) by an Extraction/Microfiltration/Reverse Osmosis (Nanofiltration) Process. Innov. Food Sci. Emerg. Technol. 2018, 51, 80–90. [Google Scholar] [CrossRef] Pettolino, F.A.; Walsh, C.; Fincher, G.B.; Bacic, A. Determining the Polysaccharide Composition of Plant Cell Walls. Nat. Protoc. 2012, 7, 1590–1607. [Google Scholar] [CrossRef] Tejedor-Calvo, E.; Morales, D.; Marco, P.; Venturini, M.E.; Blanco, D.; Soler-Rivas, C. Effects of Combining Electron-Beam or Gamma Irradiation Treatments with Further Storage under Modified Atmospheres on the Bioactive Compounds of Tuber Melanosporum Truffles. Postharvest Biol. Technol. 2019, 155, 149–155. [Google Scholar] [CrossRef] Malone Steverson, E.; Korus, R.A.; Admassu, W.; Heimsch, R.C. Kinetics of the Amylase System of Saccharomycopsis fibuliger. Enzym. Microb. Technol. 1984, 6, 549–554. [Google Scholar] [CrossRef] Khan, A.A.; Gani, A.; Khanday, F.A.; Masoodi, F.A. Biological and Pharmaceutical Activities of Mushroom β-Glucan Discussed as a Potential Functional Food Ingredient. Bioact. Carbohydr. Diet. Fibre 2018, 16, 1–13. [Google Scholar] [CrossRef] Khursheed, R.; Singh, S.K.; Wadhwa, S.; Gulati, M.; Awasthi, A. Therapeutic Potential of Mushrooms in Diabetes Mellitus: Role of Polysaccharides. Int. J. Biol. Macromol. 2020, 164, 1194–1205. [Google Scholar] [CrossRef] [PubMed] Wunjuntuk, K.; Ahmad, M.; Techakriengkrai, T.; Chunhom, R.; Jaraspermsuk, E.; Chaisri, A.; Kiwwongngam, R.; Wuttimongkolkul, S.; Charoenkiatkul, S. Proximate Composition, Dietary Fibre, Beta-Glucan Content, and Inhibition of Key Enzymes Linked to Diabetes and Obesity in Cultivated and Wild Mushrooms. J. Food Compos. Anal. 2022, 105, 104226. [Google Scholar] [CrossRef] Tang, Y.; Li, H.-M.; Tang, Y.-J. Comparison of Sterol Composition between Tuber Fermentation Mycelia and Natural Fruiting Bodies. Food Chem. 2012, 132, 1207–1213. [Google Scholar] [CrossRef] Yeh, C.W.; Kan, S.C.; Lin, C.C.; Shieh, C.J.; Liu, Y.C. Polyhydroxylated Steroids and Triterpenoids from an Entophytic Fungus, Hypocreales sp. NCHU01 Isolated from Tuber Magnatum. J. Taiwan. Inst. Chem. Eng. 2016, 64, 22–30. [Google Scholar] [CrossRef] Mello, A.; Murat, C.; Bonfante, P. Truffles: Much More than a Prized and Local Fungal Delicacy. FEMS Microbiol. Lett. 2006, 260, 1–8. [Google Scholar] [CrossRef] Tejedor-Calvo, E.; Marco, P.; Spègel, P.; Soler-Rivas, C. Extraction and Trapping of Truffle Flavoring Compounds into Food Matrices Using Supercritical CO2. Food Res. Int. 2023, 164, 112422. [Google Scholar] [CrossRef] [PubMed] Tejedor-Calvo, E.; Morales, D.; García-Barreda, S.; Sánchez, S.; Venturini, M.E.; Blanco, D.; Soler-Rivas, C.; Marco, P. Effects of Gamma Irradiation on the Shelf-Life and Bioactive Compounds of Tuber aestivum Truffles Packaged in Passive Modified Atmosphere. Int. J. Food Microbiol. 2020, 332, 108774. [Google Scholar] [CrossRef] [PubMed] Tejedor-Calvo, E.; Amara, K.; Reis, F.S.; Barros, L.; Martins, A.; Calhelha, R.C.; Eugenia Venturini, M.; Blanco, D.; Redondo, D.; Marco, P.; et al. Chemical Composition and Evaluation of Antioxidant, Antimicrobial and Antiproliferative Activities of Tuber and Terfezia Truffles. Food Res. Int. 2020, 140, 110071. [Google Scholar] [CrossRef] Shah, N.N.; Hokkanen, S.; Pastinen, O.; Eljamil, A.; Shamekh, S. A Study on the Fatty Acid Composition of Lipids in Truffles Selected from Europe and Africa. 3 Biotech 2020, 10, 415. [Google Scholar] [CrossRef] Yan, X.; Wang, Y.; Sang, X.; Fan, L. Nutritional Value, Chemical Composition and Antioxidant Activity of Three Tuber Species from China. AMB Express 2017, 7, 136. [Google Scholar] [CrossRef] Yadav, D.; Negi, P.S. Bioactive Components of Mushrooms: Processing Effects and Health Benefits. Food Res. Int. 2021, 148, 110599. [Google Scholar] [CrossRef] Kalogeropoulos, N.; Yanni, A.E.; Koutrotsios, G.; Aloupi, M. Bioactive Microconstituents and Antioxidant Properties of Wild Edible Mushrooms from the Island of Lesvos, Greece. Food Chem. Toxicol. 2013, 55, 378–385. [Google Scholar] [CrossRef] Muszyńska, B.; Grzywacz-Kisielewska, A.; Kała, K.; Gdula-Argasińska, J. Anti-Inflammatory Properties of Edible Mushrooms: A Review. Food Chem. 2018, 243, 373–381. [Google Scholar] [CrossRef] [PubMed] Palacios, I.; Lozano, M.; Moro, C.; D’Arrigo, M.; Rostagno, M.A.; Martínez, J.A.; García-Lafuente, A.; Guillamón, E.; Villares, A. Antioxidant Properties of Phenolic Compounds Occurring in Edible Mushrooms. Food Chem. 2011, 128, 674–678. [Google Scholar] [CrossRef] Papoutsis, K.; Zhang, J.; Bowyer, M.C.; Brunton, N.; Gibney, E.R.; Lyng, J. Fruit, Vegetables, and Mushrooms for the Preparation of Extracts with α-Amylase and α-Glucosidase Inhibition Properties: A Review. Food Chem. 2021, 338, 128119. [Google Scholar] [CrossRef] [PubMed] Zhu, Z.Y.; Zhang, J.Y.; Chen, L.J.; Liu, X.C.; Liu, Y.; Wang, W.X.; Zhang, Y.M. Comparative Evaluation of Polysaccharides Isolated from Astragalus, Oyster Mushroom, and Yacon as Inhibitors of α-Glucosidase. Chin. J. Nat. Med. 2014, 12, 290–293. [Google Scholar] [CrossRef] Cui, J.; Gu, X.; Wang, F.; Ouyang, J.; Wang, J. Purification and Structural Characterization of an α-Glucosidase Inhibitory Polysaccharide from Apricot (Armeniaca sibirica L. Lam.) Pulp. Carbohydr. Polym. 2015, 121, 309–314. [Google Scholar] [CrossRef] Tkacz, K.; Wojdyło, A.; Turkiewicz, I.P.; Bobak, Ł.; Nowicka, P. Anti-Oxidant and Anti-Enzymatic Activities of Sea Buckthorn (Hippophaë rhamnoides L.) Fruits Modulated by Chemical Components. Antioxidants 2019, 8, 618. [Google Scholar] [CrossRef] Su, C.-H.; Hsu, C.-H.; Ng, L.-T. Inhibitory Potential of Fatty Acids on Key Enzymes Related to Type 2 Diabetes. BioFactors 2013, 39, 415–421. [Google Scholar] [CrossRef] Kaewnarin, K.; Suwannarach, N.; Kumla, J.; Lumyong, S. Phenolic Profile of Various Wild Edible Mushroom Extracts from Thailand and Their Antioxidant Properties, Anti-Tyrosinase and Hyperglycaemic Inhibitory Activities. J. Funct. Foods 2016, 27, 352–364. [Google Scholar] [CrossRef] | es_ES |
| dc.description.status | Published | es_ES |
| dc.type.refereed | Refereed | es_ES |
| dc.type.specified | Article | es_ES |
| dc.bibliographicCitation.title | Foods | en |
| dc.relation.doi | https://doi.org/10.3390/foods12142724 | es_ES |
| Aparece en las colecciones: | [DOCIART] Artículos científicos, técnicos y divulgativos | |
Ficheros en este ítem:
| Fichero | Descripción | Tamaño | Formato | |
|---|---|---|---|---|
| 9948131.pdf | 1,55 MB | Adobe PDF |  Visualizar/Abrir |
Este ítem está sujeto a una licencia Creative Commons Licencia Creative Commons
La información de este repositorio es indexada en:
