Between but Not Within-Species Variation in the Distribution of Fitness Effects

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dc.bibliographicCitation.issue11es_ES
dc.bibliographicCitation.titleMolecular Biology And Evolutionen
dc.bibliographicCitation.volume40es_ES
dc.contributor.authorNotivol Paíno, Eduardoes_ES
dc.contributor.authorJames, Jenniferes_ES
dc.contributor.authorKastally, Chedlyes_ES
dc.contributor.authorBudde, Katharina B.es_ES
dc.contributor.authorGonzalez-Martinez, Santiago C.es_ES
dc.contributor.authorMilesi, Pascales_ES
dc.contributor.authorPyhäjärvi, Tanjaes_ES
dc.contributor.authorLascoux, Martines_ES
dc.contributor.authorGenTree Consortiumes_ES
dc.date.accessioned2024-05-03T11:37:46Z
dc.date.available2024-05-03T11:37:46Z
dc.date.issued2024es_ES
dc.date.updated2024-05-03T10:54:56Z
dc.description.abstractNew mutations provide the raw material for evolution and adaptation. The distribution of fitness effects (DFE) describes the spectrum of effects of new mutations that can occur along a genome, and is, therefore, of vital interest in evolutionary biology. Recent work has uncovered striking similarities in the DFE between closely related species, prompting us to ask whether there is variation in the DFE among populations of the same species, or among species with different degrees of divergence, that is whether there is variation in the DFE at different levels of evolution. Using exome capture data from six tree species sampled across Europe we characterized the DFE for multiple species, and for each species, multiple populations, and investigated the factors potentially influencing the DFE, such as demography, population divergence, and genetic background. We find statistical support for the presence of variation in the DFE at the species level, even among relatively closely related species. However, we find very little difference at the population level, suggesting that differences in the DFE are primarily driven by deep features of species biology, and those evolutionarily recent events, such as demographic changes and local adaptation, have little impact.en
dc.description.otherforest treesen
dc.description.otherDFEen
dc.description.otherdeleterious mutationsen
dc.description.otherpopulation structureen
dc.description.sponsorshipEl presente proyecto fue apoyado por el acuerdo de subvención del Programa de Investigación e Innovación Horizonte 2020 de la Unión Europea no. 676876 (Gentree)es_ES
dc.description.statusPublishedes_ES
dc.identifier.citationJames, J., Kastally, C., Budde, K. B., González-Martínez, S. C., Milesi, P., Pyhäjärvi, T., Lascoux, M., & GenTree Consortium. (2023). Between but Not Within-Species Variation in the Distribution of Fitness Effects. Molecular Biology and Evolution, 40(11), msad228. https://doi.org/10.1093/molbev/msad228
dc.identifier.issn07374038
dc.identifier.urihttp://hdl.handle.net/10532/6993
dc.language.isoenes_ES
dc.relation.doihttps://doi.org/10.1093/molbev/msad228es_ES
dc.relation.urihttps://doi.org/10.1093/molbev/msad228es_ES
dc.rightsCreative Commons Attribution-NonCommercial-NoDerivs 3.0 Spaines_ES
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
dc.subject.agrovocBosqueses
dc.subject.agrovocEspecies forestaleses
dc.subject.agrovocMutaciónes
dc.titleBetween but Not Within-Species Variation in the Distribution of Fitness Effectsen
dc.typeJournal Contribution*
dc.type.refereedRefereedes_ES
dc.type.specifiedArticlees_ES

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