Pathogenicity and Its Implications in Taxonomy: The Brucella and Ochrobactrum Case

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dc.bibliographicCitation.titlePathogensen
dc.bibliographicCitation.volume11(3)es_ES
dc.contributor.authorMoreno, Edgardoes_ES
dc.contributor.authorBlasco Martínez, José Maríaes_ES
dc.contributor.authorLetesson, Jean Jacqueses_ES
dc.contributor.authorGorvel, Jean Pierrees_ES
dc.contributor.authorMoriyón Uria, Ignacioes_ES
dc.coverage.spatialCiencia animales_ES
dc.date.accessioned2022-03-31T07:06:15Z
dc.date.available2022-03-31T07:06:15Z
dc.date.issued2022es_ES
dc.description.abstractThe intracellular pathogens of the genus Brucella are phylogenetically close to Ochrobactrum, a diverse group of free-living bacteria with a few species occasionally infecting medically compromised patients. A group of taxonomists recently included all Ochrobactrum organisms in the genus Brucella based on global genome analyses and alleged equivalences with genera such as Mycobacterium. Here, we demonstrate that such equivalencies are incorrect because they overlook the complexities of pathogenicity. By summarizing Brucella and Ochrobactrum divergences in lifestyle, structure, physiology, population, closed versus open pangenomes, genomic traits, and pathogenicity, we show that when they are adequately understood, they are highly relevant in taxonomy and not unidimensional quantitative characters. Thus, the Ochrobactrum and Brucella differences are not limited to their assignments to different “risk-groups”, a biologically (and hence, taxonomically) oversimplified description that, moreover, does not support ignoring the nomen periculosum rule, as proposed. Since the epidemiology, prophylaxis, diagnosis, and treatment are thoroughly unrelated, merging free-living Ochrobactrum organisms with highly pathogenic Brucella organisms brings evident risks for veterinarians, medical doctors, and public health authorities who confront brucellosis, a significant zoonosis worldwide. Therefore, from taxonomical and practical standpoints, the Brucella and Ochrobactrum genera must be maintained apart. Consequently, we urge researchers, culture collections, and databases to keep their canonical nomenclature.en
dc.description.statusPublishedes_ES
dc.identifier.citationPathogens, vol. 11, num. 3, (2022)
dc.identifier.urihttp://hdl.handle.net/10532/5833
dc.language.isoenes_ES
dc.relation.doi10.3390/pathogens11030377es_ES
dc.relation.urihttps://www.mdpi.com/2076-0817/11/3/377es_ES
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 España*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es/*
dc.subject.agrovocBrucellaes
dc.subject.agrovocBrucelosises
dc.subject.agrovocPatogenicidades
dc.subject.agrovocGenomases
dc.titlePathogenicity and Its Implications in Taxonomy: The Brucella and Ochrobactrum Caseen
dc.typeJournal Contribution*
dc.type.refereedRefereedes_ES
dc.type.specifiedArticlees_ES

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