Application of Pressurized Liquid Extractions to Obtain Bioactive Compounds from Tuber aestivum and Terfezia claveryi

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dc.bibliographicCitation.titleFoodsen
dc.bibliographicCitation.volume11(3)es_ES
dc.contributor.authorTejedor Calvo, Evaes_ES
dc.contributor.authorGarcía Barreda, Sergies_ES
dc.contributor.authorSánchez Durán, Sergioes_ES
dc.contributor.authorMorte, Asunciónes_ES
dc.contributor.authorSiles Sánchez, María de las Nieveses_ES
dc.contributor.authorSoler Rivas, Cristinaes_ES
dc.contributor.authorSantoyo, Susanaes_ES
dc.contributor.authorMarco Montori, Pedroes_ES
dc.coverage.spatialCiencia vegetales_ES
dc.date.accessioned2022-01-26T10:40:18Z
dc.date.available2022-01-26T10:40:18Z
dc.date.issued2022es_ES
dc.description.abstractA PLE (pressurized liquid extraction) method was adjusted following a full-factorial experimental design to obtain bioactive-enriched fractions from Tuber aestivum and Terfezia claveryi. Temperature, time and solvent (water, ethanol and ethanol–water 1:1) parameters were investigated. The response variables investigated were: obtained yield and the levels of total carbohydrate (compounds, β-glucans, chitin, proteins, phenolic compounds and sterols). Principal component analysis indicated water solvent and high temperatures as more adequate parameters to extract polysaccharide-rich fractions (up to 68% of content), whereas ethanol was more suitable to extract fungal sterols (up to 12.5% of content). The fractions obtained at optimal conditions (16.7 MPa, 180 °C, 30 min) were able to protect Caco2 cells from free radical exposure, acting as antioxidants, and were able to reduce secretion of pro-inflammatory cytokines in vitro: IL-6 (50%), and TNFα (80% only T. claveryi ethanol extract), as well as reduce high inhibitory activity (T. aestivum IC50: 9.44 mG/mL).en
dc.description.statusPublishedes_ES
dc.identifier.citationFoods, vol. 11, num. 3, (2022)
dc.identifier.urihttp://hdl.handle.net/10532/5722
dc.language.isoenes_ES
dc.relation.doi10.3390/foods11030298es_ES
dc.relation.urihttps://www.mdpi.com/2304-8158/11/3/298es_ES
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 España*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es/*
dc.subject.agrovocTuberes
dc.subject.agrovocTerfeziaes
dc.subject.agrovocInmunoestimulaciónes
dc.subject.agrovocDiseño experimentales
dc.subject.agrovocMetodologíaes
dc.titleApplication of Pressurized Liquid Extractions to Obtain Bioactive Compounds from Tuber aestivum and Terfezia claveryien
dc.typeJournal Contribution*
dc.type.refereedRefereedes_ES
dc.type.specifiedArticlees_ES

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