Rutin-stevioside and related conjugates for potential control of grapevine trunk diseases

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dc.bibliographicCitation.endpage77es_ES
dc.bibliographicCitation.stpage65es_ES
dc.bibliographicCitation.titlePhytopathologia Mediterraneaen
dc.bibliographicCitation.volume61(1)es_ES
dc.contributor.authorBuzón Durán, Lauraes_ES
dc.contributor.authorLanga Lomba, Nataliaes_ES
dc.contributor.authorGonzález García, Vicentees_ES
dc.contributor.authorCasanova Gascón, Josées_ES
dc.contributor.authorSánchez Hernández, Evaes_ES
dc.contributor.authorMartín Gil, Jesúses_ES
dc.contributor.authorMartín Ramos, Pabloes_ES
dc.coverage.spatialSistemas Agrícolas, Forestales y Medio Ambiente - SAFMAes_ES
dc.date.accessioned2022-03-31T08:04:17Z
dc.date.available2022-03-31T08:04:17Z
dc.date.issued2022es_ES
dc.description.abstractFlavonoids and phenolic acids play roles in grapevine defence against pathogens causing grapevine trunk diseases (GTDs). Rutin is a major flavonoid in vegetative organs of the grapevines, and this compound, unlike other flavonoids, is non-toxic and non-oxidizable. Rutin was assayed in vitro and in vivo against two Botryosphaeriaceae taxa. The limited bioavailability of this compound was circumvented by conjugation with stevioside, a glycoside obtained from Stevia rebaudiana. Clear synergistic effects were observed for the stevioside-rutin adduct, resulting in EC50 and EC90 values of 306.0 and 714.9 μg·mL-1 against Neofusicoccum parvum and 241.6 and 457.8 μg·mL-1 against Dothiorella viticola. In greenhouse experiments, moderate inhibition of N. parvum growth and complete inhibition of D. viticola were observed. These inhibitory effects were greater than those of ferulic acid, which has been considered the most effective phenolic acid against GTDs. Conjugation with stevioside provided solubility enhancement of rutin, paving the way to the design of glycopesticides based on rutin-rich plant extracts as promising antifungals against GTDs.en
dc.description.statusPublishedes_ES
dc.identifier.citationPhytopathologia Mediterranea, vol. 61, num. 1, pp. 65-77, (2022)
dc.identifier.urihttp://hdl.handle.net/10532/5835
dc.language.isoenes_ES
dc.relation.doi10.36253/phyto-13108es_ES
dc.relation.urihttps://oajournals.fupress.net/index.php/pm/article/view/13108es_ES
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 España*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es/*
dc.subject.agrovocEnfermedades fungosases
dc.subject.agrovocMaderaes
dc.subject.agrovocVitis viníferaes
dc.subject.agrovocControl de enfermedadeses
dc.titleRutin-stevioside and related conjugates for potential control of grapevine trunk diseasesen
dc.typeJournal Contribution*
dc.type.refereedRefereedes_ES
dc.type.specifiedArticlees_ES

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