Análisis de la utilidad para estudios genómicos del ‘Illumina Ovine SNP50BeadChip’ en razas ovinas españolas
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Date
2011
Authors
Gutiérrez Gil, B.García Gómez, E.
Suárez Vega, A.
Sánchez, J.P.
Kijas, J.
Calvo Lacosta, Jorge Hugo
International Sheep Genomics Consortium (ISGC)
Arranz, J.J.
Journal Title
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Typology
conferenceObjectAbstract
During the development of the Sheep HapMap project, ewes from 6 breeds
(Awassi, Merino, Poll Dorset, Romney, Scottish Blackface and Texel) were used to obtain
the sequence of the ovine genome and look for variability. The Ovine SNP50BeadChip
(Illumina) was then genotyped in 71 breeds, four of which were Spanish breeds. In some
species (pig and cow) a bias has been described when testing a SNP Chip in different
breeds. The aim of this study was to analyse this possible bias due to the sheep breed in the
Spanish populations included in the Sheep HapMap project. For this purpose, we estimated
for both, the breeds used in the Chip development and the Spanish populations the following
parameters: MAF within and between breeds, gene diversity, individual heterozygosity and
average proportion of alleles shared within population. The results obtained in Spanish breed
were similar to those observed in the six breeds sequenced during the SNP-chip
development. These findings support the value of Ovine SNP50BeadChip for genomic
analysis in Spanish sheep breeds.
Description
Keywords
Sheep, Ovine SNP-chip, Genetic variability
Bibliographic citation
Gutiérrez-Gil, B., García-Gámez, E., Suárez-Vega, A., Sánchez J.P. Kijas, J., Calvo, J.H. International Sheep Genomics Consortium (ISGC) y Arranz, J.J. “Análisis de la utilidad para estudios genómicos del ‘Illumina Ovine SNP50BeadChip’ en razas ovinas españolas”. En: 41 Jornadas de Estudio. XIV Jornadas sobre Producción Animal. AIDA. Zaragoza, España, 17 y 18 de mayo de 2011, pp.527-529. ISBN: 978-84-615-0062-8
Other field subjects
OvinosRazas indígenas
Variación genética
Producción y sanidad animal