Studies of genetic diversity and genome‐wide association for vitamin C content in lettuce (Lactuca sativa L.) using high‐throughput SNP arrays

Simple item page
dc.bibliographicCitation.stpagee20518es_ES
dc.bibliographicCitation.titlePlant Genomeen
dc.contributor.authorMedina Lozano, Inéses_ES
dc.contributor.authorBertolín Pardos, Juan Ramónes_ES
dc.contributor.authorPlieske, Jörges_ES
dc.contributor.authorGanal, Martines_ES
dc.contributor.authorGnad, Heikees_ES
dc.contributor.authorDíaz Bermúdez, Auroraes_ES
dc.date.accessioned2024-11-07T06:35:10Z
dc.date.available2024-11-07T06:35:10Z
dc.date.issued2024es_ES
dc.date.updated2024-10-29T09:59:02Z
dc.description.abstractLettuce (Lactuca sativa L.) is a source of beneficial compounds though they are generally present in low quantities. We used 40K Axiom and 9K Infinium SNP (single nucleotide polymorphism) arrays to (i) explore the genetic variability in 21 varieties and (ii) carry out genome-wide association studies (GWAS) of vitamin C content in21 varieties and a population of 205 plants from the richest variety in vitamin C (‘Lechuga del Pirineo’). Structure and phylogenetic analyses showed that the group formed mainly by traditional varieties was the most diverse, whereas the red commercial varieties clustered together and very distinguishably apart from the rest. GWAS consistently detected, in a region of chromosome 2, several SNPs related to dehydroascorbic acid (a form of vitamin C) content using three different methods to assess population structure, subpopulation membership coefficients, multidimensional scaling, and principal component analysis. The latter detected the highest number of SNPs (17) and the most significantly associated, 12 of them showing a high linkage disequilibrium with the lead SNP. Among the 84 genes in the region, some have been reported to be related to vitamin C content or antioxidant status in other crops either directly, like those encoding long non-coding RNA, several F-box proteins, and a pectinesterase/pectinesterase inhibitor, or indirectly, like extensin-1-like protein and endoglucanase 2 genes. The involvement of other genes identified within the region in vitamin C levels needs to be further studied. Understanding the genetic control of such an important quality trait in lettuce becomes very relevant from a breeding perspective.en
dc.description.sponsorshipThis work was funded by the projects PID2022-138484OR-I00 from the Spanish Ministry of Science and Innovation (MCIN) and State Research Agency (AEI) and AGROALNEXT BIODIVERSA from the MCIN with funding from European Union (EU) NextGenerationEU: PRTR-C17.I1, and by the European Social Fund from the EU through the Government of Aragon (A12_23R: “Grupo de investigación en fruticultura: caracterización, adaptación y mejora genética”). Inés Medina-Lozano was supported by a predoctoral contract for training doctors from the Spanish Ministry of Science, Innovation and Universities (MCIU) and the AEI.es_ES
dc.description.statusPublishedes_ES
dc.identifier.citationMedina-Lozano, I., Bertolín, J. R., Plieske, J., Ganal, M., Gnad, H., & Díaz, A. (2024). Studies of genetic diversity and genome-wide association for vitamin C content in lettuce (Lactuca sativa L.) using high-throughput SNP arrays. The Plant Genome, e20518. https://doi.org/10.1002/tpg2.20518
dc.identifier.issn19403372
dc.identifier.urihttp://hdl.handle.net/10532/7333
dc.language.isoenes_ES
dc.relation.doihttps://doi.org/10.1002/tpg2.20518es_ES
dc.relation.urihttps://doi.org/10.1002/tpg2.20518es_ES
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internationales_ES
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject.agrovocLactuca sativaes
dc.subject.agrovocPolimorfismo de un solo nucleótidoes
dc.subject.agrovocÁcido ascórbicoes
dc.subject.agrovocEstudios de asociación del genoma completoes
dc.subject.agrovocDiversidad genética (como recurso)es
dc.subject.otherÁcido Ascórbico
dc.subject.otherDiversidad Genética (Como Recurso)
dc.subject.otherEstudios de asociación del genoma completo
dc.subject.otherLactuca Sativa
dc.subject.otherPolimorfismo De Un Solo Nucleótido
dc.titleStudies of genetic diversity and genome‐wide association for vitamin C content in lettuce (Lactuca sativa L.) using high‐throughput SNP arraysen
dc.typeJournal Contribution*
dc.type.refereedRefereedes_ES
dc.type.specifiedArticlees_ES

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
10088492.pdf
Size:
1.42 MB
Format:
Adobe Portable Document Format
Description:
Artículo
Download

Collections

Artículos científicos, técnicos y divulgativos