Estudio de la estructura poblacional de cuatro razas ovinas españolas mediante un chip de SNPs
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Date
2011
Authors
García Gámez, E.Gutiérrez Gil, B.
Kijas, J.
Calvo Lacosta, Jorge Hugo
International Sheep Genomics Consortium (ISGC)
Arranz, J.J.
Journal Title
Journal ISSN
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conferenceObjectAbstract
Modern genomic tools allow genome-wide association studies (GWAS) to find
genes underlying economically important traits in animals. In human, these studies have
found many associations that cannot be always replicated. One of the reasons for this is the
presence of population stratification in groups considered to be homogeneous. The objective
of this work was to study the genetic structure of four Spanish sheep breeds (Castellana,
Churra, Ojalada and Rasa Aragonesa) included in the Sheep HapMap. We selected 154
SNPs from the Ovine SNP50BeadChip, using PLINK options. Five independent analyses
were made with STRUCTURE software to calculate the most likely number of clusters. The
closest breeds were Ojalada and Rasa Aragonesa; Awassi was the most different when
compared with any of the Spanish breeds. Population structure analysis revealed K=6 to be
the most likely number of clusters. According to these results, Awassi was the most different
breed (K=2), whereas among the Spanish populations, Churra was the only one clustering
separately from the rest (K=3). Moreover, there were more differences within this breed than
among the others (K=6). This study represents a first approach to assess/study population
structure in Spanish sheep breeds and understand how these populations will behave in
future GWAS
Description
Keywords
Population structure, Spanish sheep, SNP-chip
Bibliographic citation
García-Gámez, E., Gutiérrez-Gil, B., Kijas, J., Calvo, J.H., International Sheep Genomics Consortium (ISGC), Arranz, J.J. “Estudio de la estructura poblacional de cuatro razas ovinas españolas mediante un chip de SNPs”. En: 41 Jornadas de Estudio. XIV Jornadas sobre Producción Animal. AIDA. Zaragoza, España, 17 y 18 de mayo de 2011, pp.530-532. ISBN: 978-84-615-0062-8
Other field subjects
Mejora genéticaRazas indígenas
Ovinos
Producción y sanidad animal